What drugs will interact with Promethazine?

July 16, 2008 – 4:52 pm

Advices:

Promethazine, Phenergan is used in relieving allergy symptoms, including hives and nasal congestionprevent and control pain and nausea during and after surgery. It is also used to help produce light sleep, and for the prevention of motion sickness. Promethazine is a phenothiazine antihistamine. It works by blocking the sights where histamine acts.

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Many drugs can interact with promethazine. Below is just a partial list. Tell your doctor if you are using:

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sedatives or anxiety medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);
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antidepressants such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil);
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narcotic pain medicines such as meperidine (Demerol), morphine (MS Contin, MSIR), propoxyphene (Darvon, Darvocet), hydrocodone (Lortab, Vicodin), oxycodone (Percocet, Percodan), fentanyl (Duragesic), codeine (Fiorinal, Fioricet, Tylenol #3);
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phenobarbital (Luminal), amobarbital (Amytal) or secobarbital (Seconal);
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an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or
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atropine (Donnatal, and others), belladonna, clidinium (Quarzan), dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), methscopolamine (Pamine), and scopolamine (Transderm-Scop).

This list is not complete and there may be other drugs that can interact with promethazine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Promethazine

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