Promethazine Description
July 16, 2008 – 5:01 pm
Advices:
Promethazine, Phenergan is used in relieving allergy symptoms, including hives and nasal congestionprevent and control pain and nausea during and after surgery. It is also used to help produce light sleep, and for the prevention of motion sickness. Promethazine is a phenothiazine antihistamine. It works by blocking the sights where histamine acts.
Each tablet of Phenergan contains 12.5 mg, 25 mg, or 50 mg promethazine HCl. The inactive ingredients present are lactose, magnesium stearate, and methylcellulose. Each dosage strength also contains the following:
12.5 mg-FD&C Yellow 6 and saccharin sodium;
25 mg-saccharin sodium;
50 mg-FD&C Red 40.
Each rectal suppository of Phenergan contains 12.5 mg, 25 mg, or 50 mg promethazine HCl with ascorbyl palmitate, silicon dioxide, white wax, and cocoa butter. Phenergan Suppositories are for rectal administration only.
Promethazine HCl is a racemic compound; the empirical formula is C17H20N2S•HCl and its molecular weight is 320.88.
Promethazine HCl occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is freely soluble in water and soluble in alcohol.